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首页- Products - Others - Other Targets - (E)-GABAB receptor antagonist 1

(E)-GABAB receptor antagonist 1

CAS No. 1611483-29-4

(E)-GABAB receptor antagonist 1 ( —— )

产品货号. M26186 CAS No. 1611483-29-4

(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥2373 有现货
5MG ¥3621 有现货
10MG ¥5338 有现货
25MG ¥7995 有现货
50MG ¥11178 有现货
100MG ¥15309 有现货
500MG ¥30699 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    (E)-GABAB receptor antagonist 1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.
  • 产品描述
    (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. GABAB receptor antagonist 1 (compound 14) is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.(In Vitro):(E)-GABAB receptor antagonist 1 reduces the maximum effect of IP3 in HEK293 cells overexpressing GABAB receptor and Gqi9 protein induced by agonist GABA, but does not alter EC50.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Adenine phosphoribosyltransferase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1611483-29-4
  • 分子量
    304.4
  • 分子式
    C18H24O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(O)C(/C=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=O.[(E)]
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Edamura K, et al. No self-injurious behavior was found in HPRT-deficient mice treated with 9-ethyladenine. Pharmacol Biochem Behav. 1998 Oct;61(2):175-9.
产品手册
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